Role of ceramide-to-dihydroceramide ratios for insulin resistance and non-alcoholic fatty liver disease in humans

INTRODUCTION: Sphingolipid accumulation has been linked to obesity, type 2 diabetes and non-alcoholic fatty liver disease (NAFLD). A recent study showed that depletion of dihydroceramide desaturase-1 (DES-1) in adipose and/or liver tissue decreases ceramide-to-dihydroceramide ratios (ceramide/dihydr...

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Detalhes bibliográficos
Publicado no:BMJ Open Diabetes Res Care
Main Authors: Apostolopoulou, Maria, Gordillo, Ruth, Gancheva, Sofiya, Strassburger, Klaus, Herder, Christian, Esposito, Irene, Schlensak, Matthias, Scherer, Philipp E, Roden, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682191/
https://ncbi.nlm.nih.gov/pubmed/33219119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2020-001860
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