Characterization of the dual functional effects of heat shock proteins (HSPs) in cancer hallmarks to aid development of HSP inhibitors

BACKGROUND: Heat shock proteins (HSPs), a representative family of chaperone genes, play crucial roles in malignant progression and are pursued as attractive anti-cancer therapeutic targets. Despite tremendous efforts to develop anti-cancer drugs based on HSPs, no HSP inhibitors have thus far reache...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Zhang, Zhao, Jing, Ji, Ye, Youqiong, Chen, Zhiao, Jing, Ying, Li, Shengli, Hong, Wei, Ruan, Hang, Liu, Yaoming, Hu, Qingsong, Wang, Jun, Li, Wenbo, Lin, Chunru, Diao, Lixia, Zhou, Yubin, Han, Leng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682077/
https://ncbi.nlm.nih.gov/pubmed/33225964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-020-00795-6
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