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Diesel exhaust impairs TREM2 to dysregulate neuroinflammation
BACKGROUND: Air pollution has been linked to neurodegenerative diseases, including Alzheimer’s disease (AD), and the underlying neuroimmune mechanisms remain poorly understood. TREM2 is a myeloid cell membrane receptor that is a key regulator of disease-associated microglia (DAM) cells, where loss-o...
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| Publicado no: | J Neuroinflammation |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7682066/ https://ncbi.nlm.nih.gov/pubmed/33222683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-02017-7 |
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