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The circular RNA circ-ERBIN promotes growth and metastasis of colorectal cancer by miR-125a-5p and miR-138-5p/4EBP-1 mediated cap-independent HIF-1α translation

BACKGROUND: Circular RNA (circRNAs) and hypoxia have been found to play the key roles in the pathogenesis and progression of cancer including colorectal cancer (CRC). However, the expressions and functions of the specific circRNAs in regulating hypoxia-involved CRC metastasis, and the circRNAs that...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cancer
Hauptverfasser: Chen, Liang-Yan, Wang, Lian, Ren, Yue-Xiang, Pang, Zheng, Liu, Yao, Sun, Xiao-Dong, Tu, Jian, Zhi, Zheng, Qin, Yan, Sun, Li-Na, Li, Jian-Ming
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682012/
https://ncbi.nlm.nih.gov/pubmed/33225938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-01272-9
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