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Inhibitor for protein disulfide-isomerase family A member 3 enhances the antiproliferative effect of inhibitor for mechanistic target of rapamycin in liver cancer: An in vitro study on combination treatment with everolimus and 16F16

mTOR is involved in the proliferation of liver cancer. However, the clinical benefit of treatment with mTOR inhibitors for liver cancer is controversial. Protein disulfide isomerase A member 3 (PDIA3) is a chaperone protein, and it supports the assembly of mTOR complex 1 (mTORC1) and stabilizes sign...

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Dettagli Bibliografici
Pubblicato in:Oncol Lett
Autori principali: Kaneya, Yohei, Takata, Hideyuki, Wada, Ryuichi, Kure, Shoko, Ishino, Kousuke, Kudo, Mitsuhiro, Kondo, Ryota, Taniai, Nobuhiko, Ohashi, Ryuji, Yoshida, Hiroshi, Naito, Zenya
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681208/
https://ncbi.nlm.nih.gov/pubmed/33240434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.12289
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