The ATP synthase inhibition induces an AMPK-dependent glycolytic switch of mesenchymal stem cells that enhances their immunotherapeutic potential

Objectives: Mesenchymal Stem/Stromal Cells (MSC) are promising therapeutic tools for inflammatory diseases due to their potent immunoregulatory capacities. Their suppressive activity mainly depends on inflammatory cues that have been recently associated with changes in MSC bioenergetic status toward...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Contreras-Lopez, Rafael, Elizondo-Vega, Roberto, Luque-Campos, Noymar, Torres, María José, Pradenas, Carolina, Tejedor, Gautier, Paredes-Martínez, María José, Vega-Letter, Ana María, Campos-Mora, Mauricio, Rigual-Gonzalez, Yandi, Oyarce, Karina, Salgado, Magdiel, Jorgensen, Christian, Khoury, Maroun, Garcia-Robles, María de los Ángeles, Altamirano, Claudia, Djouad, Farida, Luz-Crawford, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681096/
https://ncbi.nlm.nih.gov/pubmed/33391485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.51631
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