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CR reprograms acetyl‐CoA metabolism and induces long‐chain acyl‐CoA dehydrogenase and CrAT expression

Calorie restriction (CR), an age delaying diet, affects fat oxidation through poorly understood mechanisms. We investigated the effect of CR on fat metabolism gene expression and intermediate metabolites of fatty acid oxidation in the liver. We found that CR changed the liver acylcarnitine profile:...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Mezhnina, Volha, Pearce, Ryan, Poe, Allan, Velingkaar, Nikkhil, Astafev, Artem, Ebeigbe, Oghogho P., Makwana, Kuldeep, Sandlers, Yana, Kondratov, Roman V.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681051/
https://ncbi.nlm.nih.gov/pubmed/33105059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13266
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