Overlapping function of Hrd1 and Ste24 in translocon quality control provides robust channel surveillance

Translocation of proteins across biological membranes is essential for life. Proteins that clog the endoplasmic reticulum (ER) translocon prevent the movement of other proteins into the ER. Eukaryotes have multiple translocon quality control (TQC) mechanisms to detect and destroy proteins that persi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Runnebohm, Avery M., Richards, Kyle A., Irelan, Courtney Broshar, Turk, Samantha M., Vitali, Halie E., Indovina, Christopher J., Rubenstein, Eric M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Accelerated Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681017/
https://ncbi.nlm.nih.gov/pubmed/33033070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC120.016191
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