GGPP depletion initiates metaflammation through disequilibrating CYB5R3-dependent eicosanoid metabolism

Metaflammation is a primary inflammatory complication of metabolic disorders characterized by altered production of many inflammatory cytokines, adipokines, and lipid mediators. Whereas multiple inflammation networks have been identified, the mechanisms by which metaflammation is initiated have long...

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Udgivet i:J Biol Chem
Main Authors: Wei, Lisha, Zheng, Yan-Yan, Sun, Jie, Wang, Pei, Tao, Tao, Li, Yeqiong, Chen, Xin, Sang, Yongjuan, Chong, Danyang, Zhao, Wei, Zhou, Yuwei, Wang, Ye, Jiang, Zhihui, Qiu, Tiantian, Li, Chao-Jun, Zhu, Min-Sheng, Zhang, Xuena
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2020
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681012/
https://ncbi.nlm.nih.gov/pubmed/32913122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015020
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