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Integrin α3β1 on tumor keratinocytes is essential to maintain tumor growth and promotes a tumor-supportive keratinocyte secretome.
Development of integrin-targeted cancer therapies is hindered by incomplete understanding of integrin function in tumor cells and the tumor microenvironment. Previous studies showed that mice with epidermis-specific deletion of the α3 integrin subunit fail to form skin tumors during two-step chemica...
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| Publicat a: | J Invest Dermatol |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7680721/ https://ncbi.nlm.nih.gov/pubmed/32454065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2020.05.080 |
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