Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine

Patient-derived xenograft (PDX) tumor models represent a valuable platform for identifying new biomarkers and novel targets, to evaluate therapy response and resistance mechanisms. This study aimed at establishment, characterization and therapy testing of colorectal carcinoma-derived PDX. We generat...

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發表在:Neoplasia
Main Authors: Rivera, Maria, Fichtner, Iduna, Wulf-Goldenberg, Annika, Sers, Christine, Merk, Johannes, Patone, Giannino, Alp, Keziban M., Kanashova, Tamara, Mertins, Philipp, Hoffmann, Jens, Stein, Ulrike, Walther, Wolfgang
格式: Artigo
語言:Inglês
出版: Neoplasia Press 2020
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Original article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680704/
https://ncbi.nlm.nih.gov/pubmed/33212364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2020.11.005
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