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Botulinum toxin blocks mast cells and prevents rosacea like inflammation

BACKGROUND: Rosacea is a chronic inflammatory skin condition whose etiology has been linked to mast cells and the antimicrobial peptide cathelicidin LL-37. Individuals with refractory disease have demonstrated clinical benefit with periodic injections of onabotulinum toxin, but the mechanism of acti...

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Detalles Bibliográficos
Publicado en:J Dermatol Sci
Main Authors: Choi, Jae Eun, Werbel, Tyler, Wang, Zhenping, Wu, Chia Chi, Yaksh, Tony L., Nardo, Anna Di
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680644/
https://ncbi.nlm.nih.gov/pubmed/30658871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdermsci.2018.12.004
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