Shortwave infrared polymethine fluorophores matched to excitation lasers enable noninvasive, multicolor in vivo imaging in real time

High resolution, multiplexed experiments are a staple in cellular imaging. Analogous experiments in animals are challenging, however, due to significant scattering and autofluorescence in tissue at visible (VIS, 350–700 nm) and near-infrared (NIR, 700–1000 nm) wavelengths. Here, we enable real-time,...

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Udgivet i:Nat Chem
Main Authors: Cosco, Emily D., Spearman, Anthony L., Ramakrishnan, Shyam, Lingg, Jakob G. P., Saccomano, Mara, Pengshung, Monica, Arús, Bernardo A., Wong, Kelly C. Y., Glasl, Sarah, Ntziachristos, Vasilis, Warmer, Martin, McLaughlin, Ryan R., Bruns, Oliver T., Sletten, Ellen M.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680456/
https://ncbi.nlm.nih.gov/pubmed/33077925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-020-00554-5
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