Clinical evaluation of [(18)F] JNJ-64326067, a novel candidate PET tracer for the detection of tau pathology in Alzheimer’s disease

PURPOSE: The accumulation of misfolded tau is a common feature of several neurodegenerative disorders, with Alzheimer’s disease (AD) being the most common. Earlier we identified JNJ-64326067, a novel isoquinoline derivative with high affinity and selectivity for tau aggregates from human AD brain. W...

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Veröffentlicht in:Eur J Nucl Med Mol Imaging
Hauptverfasser: Schmidt, Mark E., Janssens, Luc, Moechars, Diederik, Rombouts, Frederik J. R., Timmers, Maarten, Barret, Olivier, Constantinescu, Cristian C., Madonia, Jennifer, Russell, David S., Sandiego, Christine M., Kolb, Hartmuth
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680304/
https://ncbi.nlm.nih.gov/pubmed/32535652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-020-04880-1
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