STAT1 Dissociates Adipose Tissue Inflammation From Insulin Sensitivity in Obesity

Obesity fosters low-grade inflammation in white adipose tissue (WAT) that may contribute to the insulin resistance that characterizes type 2 diabetes. However, the causal relationship of these events remains unclear. The established dominance of STAT1 function in the immune response suggests an obli...

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Vydáno v:Diabetes
Hlavní autoři: Cox, Aaron R., Chernis, Natasha, Bader, David A., Saha, Pradip K., Masschelin, Peter M., Felix, Jessica B., Sharp, Robert, Lian, Zeqin, Putluri, Vasanta, Rajapakshe, Kimal, Kim, Kang Ho, Villareal, Dennis T., Armamento-Villareal, Reina, Wu, Huaizhu, Coarfa, Cristian, Putluri, Nagireddy, Hartig, Sean M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2020
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679774/
https://ncbi.nlm.nih.gov/pubmed/32994273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db20-0384
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