Adjuvant role of Ocimum sanctum hydroalcoholic extract with carbamazepine and phenytoin in experimental model of acute seizures

PURPOSE: This study assessed adjuvant potential of Ocimum sanctum hydroalcoholic extract (OSHE) with antiepileptic drugs (AEDs) carbamazepine (CBZ) and phenytoin (PHT) in maximal electroshock seizure (MES) model in male Wistar rats. MATERIAL AND METHODS: Pharmacodynamic effect of OSHE (1000 mg/kg) w...

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Publicat a:Saudi Pharm J
Autors principals: Sarangi, Sudhir Chandra, Pattnaik, Soumya Sucharita, Joshi, Dipesh, Chandra, P. Prarthana, Kaleekal, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679441/
https://ncbi.nlm.nih.gov/pubmed/33250652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2020.09.010
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