Cepharanthine induces ROS stress in glioma and neuronal cells via modulation of VDAC permeability

Cepharanthine (CEP) is a bisbenzylisoquinoline alkaloid. Molecular dynamics studies show that CEP interacts with Voltage-dependent anion channel (VDAC), inducing the voltage-independent channel narrowing. In the new conformation, transport between mitochondria and cytoplasm is altered, which leads t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Saudi Pharm J
Main Authors: Cierluk, Karolina, Szlasa, Wojciech, Rossowska, Joanna, Tarek, Mounir, Szewczyk, Anna, Saczko, Jolanta, Kulbacka, Julita
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679435/
https://ncbi.nlm.nih.gov/pubmed/33250643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2020.08.026
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados