The curious case of Merkel cell carcinoma: epigenetic youth and lack of pluripotency

Merkel cell carcinoma (MCC) is a very rare, but highly aggressive skin cancer which occurs mainly in elderly patients. MCC cells show an expression pattern of three cell lineages: epithelial, neuroendocrine, and B-cell progenitor. This trilinear expression pattern suggests stemness activity in MCC....

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Chteinberg, Emil, Vogt, Julia, Kolarova, Julia, Bormann, Felix, van den Oord, Joost, Speel, Ernst Jan, Winnepenninckx, Véronique, Kurz, Anna Kordelia, Zenke, Martin, Siebert, Reiner, zur Hausen, Axel
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7678933/
https://ncbi.nlm.nih.gov/pubmed/32475296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2020.1773096
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