LTBK-01. INO-5401 AND INO-9012 DELIVERED INTRAMUSCULARLY (IM) WITH ELECTROPORATION (EP) IN COMBINATION WITH CEMIPLIMAB (REGN2810) IN NEWLY DIAGNOSED GLIOBLASTOMA

BACKGROUND: Novel T cell-enabling therapies, in combination with checkpoint inhibition, may improve OS in GBM. INO-5401 (synthetic DNA plasmids encoding hTERT, WT-1, PSMA) plus INO-9012 (synthetic DNA plasmid encoding IL-12), and the PD-1 immune checkpoint inhibitor cemiplimab, is given to patients...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Neuro Oncol
मुख्य लेखकों: Reardon, David A, Brem, Steven, Desai, Arati Suvas, Bagley, Stephen Joseph, Kurz, Sylvia Christine, De La Fuente, Macarena Ines, Nagpal, Seema, Welch, Mary Roberta, Hormigo, Adilia, Forsyth, Peter, Mandell, Jacob, Khagi, Simon, Aiken, Robert, Walbert, Tobias, Lieberman, Frank, Portnow, Jana, Batiste, James, Carroll, Nicholas, Sylvester, Albert, Campbell, Patricia, Lowy, Israel, Dolgoter, Alex, Boyer, Jean, Kraynyak, Kimberly, Morrow, Matthew P, McMullan, Trevor, Weiner, David B, Skolnik, Jeffrey
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2020
विषय:
Late Breaking
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7678727/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.988
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