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Single-cell genomics identifies cell type–specific molecular changes in autism
Despite the clinical and genetic heterogeneity of autism, bulk gene expression studies show that changes in the neocortex of autism patients converge on common genes and pathways. However, direct assessment of specific cell types in the brain affected by autism has not been feasible until recently....
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| Publicado no: | Science |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7678724/ https://ncbi.nlm.nih.gov/pubmed/31097668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aav8130 |
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