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Human trophoblast-derived exosomes attenuate doxorubicin-induced cardiac injury by regulating miR-200b and downstream Zeb1

Human trophoblast stem cells (TSCs) have been confirmed to play a cardioprotective role in heart failure. However, whether trophoblast stem cell-derived exosomes (TSC-Exos) can protect cardiomyocytes from doxorubicin (Dox)-induced injury remains unclear. In the present study, TSC-Exos were isolated...

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Detalhes bibliográficos
Publicado no:J Nanobiotechnology
Main Authors: Ni, Jie, Liu, Yihai, Kang, Lina, Wang, Lian, Han, Zhonglin, Wang, Kun, Xu, Biao, Gu, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7678329/
https://ncbi.nlm.nih.gov/pubmed/33218341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00733-z
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