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A pitfall for machine learning methods aiming to predict across cell types

Machine learning models that predict genomic activity are most useful when they make accurate predictions across cell types. Here, we show that when the training and test sets contain the same genomic loci, the resulting model may falsely appear to perform well by effectively memorizing the average...

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Dades bibliogràfiques
Publicat a:Genome Biol
Autors principals: Schreiber, Jacob, Singh, Ritambhara, Bilmes, Jeffrey, Noble, William Stafford
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7678316/
https://ncbi.nlm.nih.gov/pubmed/33213499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02177-y
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