Tumor-derived exosomal miR-934 induces macrophage M2 polarization to promote liver metastasis of colorectal cancer

BACKGROUND: Mounting evidence has demonstrated the vital importance of tumor-associated macrophages (TAMs) and exosomes in the formation of the premetastatic niche. However, the molecular mechanisms by which tumor-derived exosomal miRNAs interact with TAMs underlying premetastatic niche formation an...

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Vydáno v:J Hematol Oncol
Hlavní autoři: Zhao, Senlin, Mi, Yushuai, Guan, Bingjie, Zheng, Binbin, Wei, Ping, Gu, Yanzi, Zhang, Zhengxiang, Cai, Sanjun, Xu, Ye, Li, Xinxiang, He, Xuefeng, Zhong, Xinyang, Li, Guichao, Chen, Zhiyu, Li, Dawei
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7678301/
https://ncbi.nlm.nih.gov/pubmed/33213490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-020-00991-2
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