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High-fat diet-induced and genetically inherited obesity differentially alters DNA methylation profile in the germline of adult male rats

BACKGROUND: Paternal obesity has been associated with reduced live birth rates. It could lead to inheritance of metabolic disturbances to the offspring through epigenetic mechanisms. However, obesity is a multifactorial disorder with genetic or environmental causes. Earlier we had demonstrated diffe...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Deshpande, Sharvari S., Nemani, Harishankar, Arumugam, Gandhimathi, Ravichandran, Avinash, Balasinor, Nafisa H.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7678167/
https://ncbi.nlm.nih.gov/pubmed/33213487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00974-7
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