The first evidence for SLFN11 expression as an independent prognostic factor for patients with esophageal cancer after chemoradiotherapy

BACKGROUND: Schlafen 11 (SLFN11) was recently identified as a dominant determinant of sensitivity to DNA-targeting agents including platinum-based drugs. SLFN11 also reportedly enhances cellular radiosensitivity. In this study, we examined the prognostic value of SLFN11 expression in esophageal squa...

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Библиографические подробности
Опубликовано в: :BMC Cancer
Главные авторы: Kagami, Takuma, Yamade, Mihoko, Suzuki, Takahiro, Uotani, Takahiro, Tani, Shinya, Hamaya, Yasushi, Iwaizumi, Moriya, Osawa, Satoshi, Sugimoto, Ken, Miyajima, Hiroaki, Baba, Satoshi, Sugimura, Haruhiko, Murai, Junko, Pommier, Yves, Furuta, Takahisa
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2020
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7678160/
https://ncbi.nlm.nih.gov/pubmed/33218331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07574-x
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