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Exploring treatment with Ribociclib alone or in sequence/combination with Everolimus in ER(+)HER2(−)Rb wild-type and knock-down in breast cancer cell lines

BACKGROUND: Breast cancer (BC) is the second most common type of cancer worldwide. Among targeted therapies for Hormone Receptor-positive (HR(+)) and Human Epidermal growth factor Receptor 2-negative (HER2(−)) BC, the Cyclin-Dependent Kinases (CDK4/6) are targeted by inhibitors such as Ribociclib (R...

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發表在:BMC Cancer
Main Authors: Marinelli, Oliviero, Romagnoli, Emanuela, Maggi, Federica, Nabissi, Massimo, Amantini, Consuelo, Morelli, Maria Beatrice, Santoni, Matteo, Battelli, Nicola, Santoni, Giorgio
格式: Artigo
語言:Inglês
出版: BioMed Central 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7678099/
https://ncbi.nlm.nih.gov/pubmed/33213401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07619-1
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