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Abundant Neural circRNA Cdr1as Is Not Indispensable for Retina Maintenance

Cdr1as is the abundant circular RNA (circRNA) in human and vertebrate retinas. However, the role of Cdr1as in the retina remains unknown. In this study, we aimed to generate a Cdr1as knockout (KO) mouse model and investigate the retinal consequences of Cdr1as loss of function. Through in situ hybrid...

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Détails bibliographiques
Publié dans:Front Cell Dev Biol
Auteurs principaux: Chen, Xue-Jiao, Li, Meng-Lan, Wang, Ya-Han, Mou, Hao, Wu, Zhen, Bao, Siqi, Xu, Ze-Hua, Zhang, Hang, Wang, Xiao-Yun, Zhang, Chang-Jun, Xue, Xiangyang, Jin, Zi-Bing
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7677238/
https://ncbi.nlm.nih.gov/pubmed/33240875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.565543
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