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Influenza virus repurposes the antiviral protein IFIT2 to promote translation of viral mRNAs

Cells infected by influenza virus mount a large-scale antiviral response and most cells ultimately initiate cell-death pathways in an attempt to suppress viral replication. We performed a CRISPR/Cas9-knockout selection designed to identify host factors required for replication following viral entry....

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Foilsithe in:Nat Microbiol
Main Authors: Tran, Vy, Ledwith, Mitchell P., Thamamongood, Thiprampai, Higgins, Christina A., Tripathi, Shashank, Chang, Max W., Benner, Christopher, Garcia-Sastre, Adolfo, Schwemmle, Martin, Boon, Adrianus C. M., Diamond, Michael S., Mehle, Andrew
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7677226/
https://ncbi.nlm.nih.gov/pubmed/32839537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-020-0778-x
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