Anti-alarmins in asthma: targeting the airway epithelium with next-generation biologics

Monoclonal antibody therapies have significantly improved treatment outcomes for patients with severe asthma; however, a significant disease burden remains. Available biologic treatments, including anti-immunoglobulin (Ig)E, anti-interleukin (IL)-5, anti-IL-5Rα and anti-IL-4Rα, reduce exacerbation r...

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Bibliographic Details
Published in:Eur Respir J
Main Authors: Porsbjerg, Celeste M., Sverrild, Asger, Lloyd, Clare M., Menzies-Gow, Andrew N., Bel, Elisabeth H.
Format: Artigo
Language:Inglês
Published: European Respiratory Society 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7676874/
https://ncbi.nlm.nih.gov/pubmed/32586879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.00260-2020
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