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Maternal antibody interference contributes to reduced rotavirus vaccine efficacy in developing countries

Rotavirus (RV) vaccine efficacy is significantly reduced in lower- and middle-income countries (LMICs) compared to high-income countries. This review summarizes current research into the mechanisms behind this phenomenon, with a particular focus on the evidence that maternal antibody (matAb) interfe...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Otero, Claire E., Langel, Stephanie N., Blasi, Maria, Permar, Sallie R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7676686/
https://ncbi.nlm.nih.gov/pubmed/33211756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009010
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