Multicellular contractility contributes to the emergence of mesothelioma nodules

Malignant pleural mesothelioma (MPM) has an overall poor prognosis and unsatisfactory treatment options. MPM nodules, protruding into the pleural cavity may have growth and spreading dynamics distinct that of other solid tumors. We demonstrate that multicellular aggregates can develop spontaneously...

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Udgivet i:Sci Rep
Main Authors: Tarnoki-Zach, Julia, Stockhammer, Paul, Isai, Dona Greta, Mehes, Elod, Szeder, Balint, Kovacs, Ildiko, Bugyik, Edina, Paku, Sandor, Berger, Walter, Thomas, Sufi Mary, Neufeld, Zoltan, Dome, Balazs, Hegedus, Balazs, Czirok, Andras
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7675981/
https://ncbi.nlm.nih.gov/pubmed/33208866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76641-x
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