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Multicellular contractility contributes to the emergence of mesothelioma nodules

Malignant pleural mesothelioma (MPM) has an overall poor prognosis and unsatisfactory treatment options. MPM nodules, protruding into the pleural cavity may have growth and spreading dynamics distinct that of other solid tumors. We demonstrate that multicellular aggregates can develop spontaneously...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Tarnoki-Zach, Julia, Stockhammer, Paul, Isai, Dona Greta, Mehes, Elod, Szeder, Balint, Kovacs, Ildiko, Bugyik, Edina, Paku, Sandor, Berger, Walter, Thomas, Sufi Mary, Neufeld, Zoltan, Dome, Balazs, Hegedus, Balazs, Czirok, Andras
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7675981/
https://ncbi.nlm.nih.gov/pubmed/33208866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76641-x
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