Comprehensive Proteomic Profiling of Urinary Exosomes and Identification of Potential Non-invasive Early Biomarkers of Alzheimer’s Disease in 5XFAD Mouse Model

BACKGROUND: Alzheimer’s disease (AD) is an incurable neurodegenerative disease characterized by irreversible progressive cognitive deficits. Identification of candidate biomarkers, before amyloid-β-plaque deposition occurs, is therefore of great importance for early intervention of AD. OBJECTIVE: To...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Song, Zhiqi, Xu, Yanfeng, Zhang, Ling, Zhou, Li, Zhang, Yu, Han, Yunlin, Li, Xianglei, Yu, Pin, Qu, Yajin, Zhao, Wenjie, Qin, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674956/
https://ncbi.nlm.nih.gov/pubmed/33250918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.565479
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