Imbalance between genomic gain and loss identifies high-risk neuroblastoma patients with worse outcomes

Survival in high-risk neuroblastoma (HR-NB) patients remains poor despite multimodal treatment. We aimed to identify HR-NB patients with worse outcomes by analyzing the genomic instability derived from segmental chromosomal aberrations. We calculated 3 genomic instability indexes for primary tumor S...

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Publicat a:Neoplasia
Autors principals: Fernández-Blanco, Beatriz, Berbegall, Ana Pilar, Martin-Vañó, Susana, Castel, Victoria, Navarro, Samuel, Noguera, Rosa
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press 2020
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Original article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674617/
https://ncbi.nlm.nih.gov/pubmed/33190090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2020.11.001
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