EHMT1 regulates Parvalbumin-positive interneuron development and GABAergic input in sensory cortical areas

Mutations in the Euchromatic Histone Methyltransferase 1 (EHMT1) gene cause Kleefstra syndrome, a rare form of intellectual disability (ID) with strong autistic traits and sensory processing deficits. Proper development of inhibitory interneurons is crucial for sensory function. Here we report a tim...

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Bibliografiske detaljer
Udgivet i:Brain Struct Funct
Main Authors: Negwer, Moritz, Piera, Karol, Hesen, Rick, Lütje, Lukas, Aarts, Lynn, Schubert, Dirk, Nadif Kasri, Nael
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2020
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674571/
https://ncbi.nlm.nih.gov/pubmed/32975655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-020-02149-9
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