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Relationship Between Hematoma Expansion Induced by Hypertension and Hyperglycemia and Blood–brain Barrier Disruption in Mice and Its Possible Mechanism: Role of Aquaporin-4 and Connexin43

We aimed to select an optimized hematoma expansion (HE) model and investigate the possible mechanism of blood–brain barrier (BBB) damage in mice. The results showed that HE occurred in the group with hypertension combined with hyperglycemia (HH-HE) from 3 to 72 h after intracerebral hemorrhage; this...

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Publicat a:Neurosci Bull
Autors principals: Chu, Heling, Gao, Zidan, Huang, Chuyi, Dong, Jing, Tang, Yuping, Dong, Qiang
Format: Artigo
Idioma:Inglês
Publicat: Springer Singapore 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674541/
https://ncbi.nlm.nih.gov/pubmed/32623691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-020-00540-4
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