Microglia control escalation of drinking in alcohol dependent mice: Genomic and synaptic drivers

BACKGROUND: Microglia, the primary immune cells of the brain, are implicated in alcohol use disorder (AUD). However, it is not known if microglial activation contributes to the transition from alcohol use to AUD or is a consequence of alcohol intake. METHODS: We investigated the role of microglia in...

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Bibliografiske detaljer
Udgivet i:Biol Psychiatry
Main Authors: Warden, Anna S., Wolfe, Sarah A., Khom, Sophia, Varodayan, Florence P., Patel, Reesha R., Steinman, Michael Q., Bajo, Michal, Montgomery, Sarah, Vlkolinsky, Roman, Nadav, Tali, Polis, Ilham, Roberts, Amanda J., Mayfield, Roy D., Harris, Robert A., Roberto, Marisa
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674270/
https://ncbi.nlm.nih.gov/pubmed/32680583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2020.05.011
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