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The abnormal firing of Purkinje cells in the knockin mouse model of DYT1 dystonia
DYT1 dystonia is an inherited movement disorder caused by a heterozygous trinucleotide (GAG) deletion in DYT1/TOR1A, coding for torsinA. Growing evidence suggests that the cerebellum plays a role in the pathogenesis of dystonia. Brain imaging of both DYT1 dystonia patients and animal models show abn...
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Publicado no: | Brain Res Bull |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2020
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7674218/ https://ncbi.nlm.nih.gov/pubmed/32976982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2020.09.011 |
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