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Functional impact of HIV-1 Tat on cells of the CNS and its role in HAND

Human immunodeficiency virus type 1 (HIV-1) transactivator of transcription (Tat) is a potent mediator involved in the development of HIV-1-associated neurocognitive disorders (HAND). Tat is expressed even in the presence of antiretroviral therapy (ART) and is able to enter the central nervous syste...

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: Marino, Jamie, Maubert, Monique E., Mele, Anthony R., Spector, Cassandra, Wigdahl, Brian, Nonnemacher, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674201/
https://ncbi.nlm.nih.gov/pubmed/32577796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-020-03561-4
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