Anakinra combined with methylprednisolone in patients with severe COVID-19 pneumonia and hyperinflammation: An observational cohort study

BACKGROUND: Immunomodulants have been proposed to mitigate severe acute respiratory syndrome coronavirus 2–induced cytokine storm, which drives acute respiratory distress syndrome in coronavirus disease 2019 (COVID-19). OBJECTIVE: We sought to determine efficacy and safety of the association of IL-1...

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Publicado en:J Allergy Clin Immunol
Autores principales: Bozzi, Giorgio, Mangioni, Davide, Minoia, Francesca, Aliberti, Stefano, Grasselli, Giacomo, Barbetta, Laura, Castelli, Valeria, Palomba, Emanuele, Alagna, Laura, Lombardi, Andrea, Ungaro, Riccardo, Agostoni, Carlo, Baldini, Marina, Blasi, Francesco, Cesari, Matteo, Costantino, Giorgio, Fracanzani, Anna Ludovica, Montano, Nicola, Monzani, Valter, Pesenti, Antonio, Peyvandi, Flora, Sottocorno, Marcello, Muscatello, Antonio, Filocamo, Giovanni, Gori, Andrea, Bandera, Alessandra
Formato: Artigo
Lenguaje:Inglês
Publicado: American Academy of Allergy, Asthma & Immunology 2021
Materias:
Covid-19
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674131/
https://ncbi.nlm.nih.gov/pubmed/33220354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2020.11.006
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