Interleukin-15 and cancer: some solved and many unsolved questions

Soluble interleukin (IL)-15 exists under two forms: as monomer (sIL-15) or as heterodimeric complex in association with sIL-15Rα (sIL-15/IL-15Rα). Both forms have been successfully tested in experimental tumor murine models and are currently undergoing investigation in phase I/II clinical trials. De...

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Foilsithe in:J Immunother Cancer
Main Authors: Fiore, Piera Filomena, Di Matteo, Sabina, Tumino, Nicola, Mariotti, Francesca Romana, Pietra, Gabriella, Ottonello, Selene, Negrini, Simone, Bottazzi, Barbara, Moretta, Lorenzo, Mortier, Erwan, Azzarone, Bruno
Formáid: Artigo
Teanga:Inglês
Foilsithe: BMJ Publishing Group 2020
Ábhair:
Review
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674108/
https://ncbi.nlm.nih.gov/pubmed/33203664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001428
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