Impact of Loading Dose of Caspofungin in Pharmacokinetic-Pharmacodynamic Target Attainment for Severe Candidiasis Infections in Patients in Intensive Care Units: the CASPOLOAD Study

This study evaluated the impact of a high loading dose of caspofungin (CAS) on the pharmacokinetics of CAS and the pharmacokinetic-pharmacodynamic (PK-PD) target attainment in patients in intensive care units (ICU). ICU patients requiring CAS treatment were prospectively included to receive a 140-mg...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Bailly, Sébastien, Gautier-Veyret, Elodie, Lê, Minh P., Bouadma, Lila, Andremont, Olivier, Neuville, Mathilde, Mourvillier, Bruno, Sonneville, Romain, Magalhaes, Eric, Lebut, Jordane, Radjou, Aguila, Smonig, Roland, Wolff, Michel, Massias, Laurent, Dupuis, Claire, Timsit, Jean-François
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674046/
https://ncbi.nlm.nih.gov/pubmed/32958709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01545-20
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