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Lysophosphatidylcholine Potentiates Antibacterial Activity of Polymyxin B

Polymyxin B, used to treat infections caused by antibiotic-resistant Gram-negative bacteria, produces nephrotoxicity at its current dosage. We show that a combination of nonbactericidal concentration of this drug and lysophosphatidylcholine (LPC) potently inhibits growth of Salmonella and at least t...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Yadav, Jitender, Ismaeel, Sana, Qadri, Ayub
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674032/
https://ncbi.nlm.nih.gov/pubmed/32988824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01337-20
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