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Transcriptional priming as a conserved mechanism of lineage diversification in the developing mouse and human neocortex

How the rich variety of neurons in the nervous system arises from neural stem cells is not well understood. Using single-cell RNA-sequencing and in vivo confirmation, we uncover previously unrecognized neural stem and progenitor cell diversity within the fetal mouse and human neocortex, including mu...

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Detalles Bibliográficos
Publicado en:Sci Adv
Main Authors: Li, Zhen, Tyler, William A., Zeldich, Ella, Santpere Baró, Gabriel, Okamoto, Mayumi, Gao, Tianliuyun, Li, Mingfeng, Sestan, Nenad, Haydar, Tarik F.
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7673705/
https://ncbi.nlm.nih.gov/pubmed/33158872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd2068
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