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Emerging systemic JAK inhibitors in the treatment of atopic dermatitis: a review of abrocitinib, baricitinib, and upadacitinib

The Janus kinases (JAK) are a group of molecules, composed of JAK1, JAK2, JAK3, and tyrosine kinase 2 (TYK2), which are key components within the JAK–signal transducers and activators of transcription pathway, where cytokine receptor signaling takes place. These molecules play a foundational role in...

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Detalhes bibliográficos
Publicado no:Drugs Context
Main Authors: Nezamololama, Novin, Fieldhouse, Keira, Metzger, Kristy, Gooderham, Melinda
Formato: Artigo
Idioma:Inglês
Publicado em: BioExcel Publishing Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7673622/
https://ncbi.nlm.nih.gov/pubmed/33240390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7573/dic.2020-8-5
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