Computational/in silico methods in drug target and lead prediction

Drug-like compounds are most of the time denied approval and use owing to the unexpected clinical side effects and cross-reactivity observed during clinical trials. These unexpected outcomes resulting in significant increase in attrition rate centralizes on the selected drug targets. These targets m...

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Bibliographic Details
Published in:Brief Bioinform
Main Authors: Agamah, Francis E, Mazandu, Gaston K, Hassan, Radia, Bope, Christian D, Thomford, Nicholas E, Ghansah, Anita, Chimusa, Emile R
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7673338/
https://ncbi.nlm.nih.gov/pubmed/31711157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbz103
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