Greater dapivirine release from the dapivirine vaginal ring is correlated with lower risk of HIV‐1 acquisition: a secondary analysis from a randomized, placebo‐controlled trial

INTRODUCTION: A vaginal ring containing 25 mg of the antiretroviral dapivirine has demonstrated efficacy in reducing women’s risk of sexually acquiring HIV‐1; however, imperfect ring use likely diluted efficacy estimates in clinical trials. The amount of dapivirine remaining in returned rings may re...

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Pubblicato in:J Int AIDS Soc
Autori principali: Brown, Elizabeth R, Hendrix, Craig W, van der Straten, Ariane, Kiweewa, Flavia M, Mgodi, Nyaradzo M, Palanee‐Philips, Thesla, Marzinke, Mark A, Bekker, Linda‐Gail, Soto‐Torres, Lydia, Hillier, Sharon L, Baeten, Jared M
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7673220/
https://ncbi.nlm.nih.gov/pubmed/33206462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jia2.25634
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