Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells

HIV broadly neutralizing antibodies (bnAbs) can suppress viremia and protect against HIV infection. However, their elicitation is made difficult by low frequencies of appropriate precursor B cell receptors and the complex maturation pathways required to generate bnAbs from these precursors. Antibody...

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書誌詳細
出版年:Nat Commun
主要な著者: Huang, Deli, Tran, Jenny Tuyet, Olson, Alex, Vollbrecht, Thomas, Tenuta, Mary, Guryleva, Mariia V., Fuller, Roberta P., Schiffner, Torben, Abadejos, Justin R., Couvrette, Lauren, Blane, Tanya R., Saye, Karen, Li, Wenjuan, Landais, Elise, Gonzalez-Martin, Alicia, Schief, William, Murrell, Ben, Burton, Dennis R., Nemazee, David, Voss, James E.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7673113/
https://ncbi.nlm.nih.gov/pubmed/33203876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19650-8
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