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Inhibition of pyruvate dehydrogenase kinase influence microbiota and metabolomic profile in pancreatic cancer xenograft mice

OBJECTIVE: Despite recent advances in treatment options, pancreatic cancer remains the most deadly major cancer. Targeting metabolism represents an emerging anti-cancer strategy. RESULTS: Metagenomic 16S analysis was employed to explore the effect of Dichloroacetate (DCA) on the composition of the f...

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Publicat a:BMC Res Notes
Autors principals: Adamberg, Kaarel, Vilu, Raivo, Pazienza, Valerio
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672971/
https://ncbi.nlm.nih.gov/pubmed/33208188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-020-05384-9
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