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Mechanisms of replication and repair in mitochondrial DNA deletion formation
Deletions in mitochondrial DNA (mtDNA) are associated with diverse human pathologies including cancer, aging and mitochondrial disorders. Large-scale deletions span kilobases in length and the loss of these associated genes contributes to crippled oxidative phosphorylation and overall decline in mit...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7672454/ https://ncbi.nlm.nih.gov/pubmed/33021629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa804 |
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