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Cell cycle regulated DNA methyltransferase: fluorescent tracking of a DNA strand-separation mechanism and identification of the responsible protein motif

DNA adenine methylation by Caulobacter crescentus Cell Cycle Regulated Methyltransferase (CcrM) is an important epigenetic regulator of gene expression. The recent CcrM-DNA cocrystal structure shows the CcrM dimer disrupts four of the five base pairs of the (5′-GANTC-3′) recognition site. We develop...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Konttinen, Olivia, Carmody, Jason, Pathuri, Sarath, Anderson, Kyle, Zhou, Xiaofeng, Reich, Norbert
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672430/
https://ncbi.nlm.nih.gov/pubmed/33053173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa844
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